M5OBP

Prompt

1.2.1.79

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. succinate-semialdehyde dehydrogenase (NADP(+)).

AI Generated Sequence

289 AAs

MSLKDPSLLRTQGYIGGEWVDASSGKTFDVINPATGEVIGTVPDMGAAETRRAIDAAHEAFAAWRDLTAKERAKVLRKLYELMLEHQDDLALLMTLEQGKPLAEAKGEIIYGASFIEWFAEEAKRIYGDTIGSPQPDKRIMVLKQPIGVCAAITPWNFPSAMITRKVGPALAAGCTMVIKPASQTPLSALAIAELAERAGFPAGVFNVVTGDAPEIGGELTSNPMVRKISFTGSTEIGKLLMEQCAKTIKRVSLELGGNAPFIVFDDADLDKAVEGAMASKYRNMGQTC

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	96.9
NLMSIM	90.0
AACOMP	93.6
Seqdif (SeqID)	23.2 (HET6618455.1)
Structdif (F-Target)	4.6 (7kqv 2)

ProtNLM

Name	Score
Succinate-semialdehyde dehydrogenase (NADP(+))	0.340
Aldehyde dehydrogenase family protein	0.187
NAD-dependent succinate-semialdehyde dehydrogenase	0.185
1.2.1.16	0.066
Succinate-semialdehyde dehydrogenase	0.057
1.2.1.79	0.024