M5D1V

Prompt

1.14.11.2

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors. procollagen-proline 4-dioxygenase.

AI Generated Sequence

500 AAs

MKWQLLLLLLAWGVLPSAAEGHLFTSISQMTDLIYTEKDLVQSLKEYIRAEEAKLAKIKSWAEKMEALTSKSTADPEGYLAHPVNAFKLVKRLNTEWPALENLVLQDMASGFIANLTVQRQFFPNEEDQTGAAKALMRLQDTYKLDTDTISKGNLPGTKYQSMLSVEDCFEMGRSVYNEGDYYHTMPWMEQVLKQLEAGEVSTTSKAQVLDYLSYAVFQLGDLHRAMELTRRLLSLDPSHERAGGNLRYFERLLAEEREKALSNQTVADTLPQTGIYERPVDYLPERDQYEMLCRGEGVKMTPRRQKRLFCRYHDGNRNPQLLIAPFKEEDEWDSPHIVRFYDVMSDDEIETIKELAKPKLARATVRDPKTGVLTVASYRVSKSSWLGEDDNPVVARVNRRMAQITGLTVKTAELLQVANYGMGGQYEPHFDFSRKDEPDAFKYLGTGNRVATFFNYLSDVEAGGATVFPELGASIWPKKGTAVFWYNLFRSGEGDYRTR

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.7
NLMSIM	95.0
AACOMP	95.0
Seqdif (SeqID)	16.0 (XP_003354320.1)
Structdif (F-Target)	6.7 (4bt8 B)

ProtNLM

Name	Score
Procollagen-proline 4-dioxygenase	0.507
1.14.11.2	0.457
Prolyl 4-hydroxylase subunit alpha-2	0.012
P4Hc domain-containing protein	0.006
Prolyl 4-hydroxylase subunit alpha 2	0.004
Prolyl 4-hydroxylase subunit alpha-1	0.001