M4XTZ

Prompt

2.5.1.60

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. protein geranylgeranyltransferase type II.

AI Generated Sequence

566 AAs

MHGRLKVKTSAEQAEAKRLEREKKLKIYQAATQAVFQKRQAGELDESVLELTTQILGANPDFATLWNYRREILQHLETQKDPEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLGRLPEPNWARELELCAKFLEVDERNFHCWDYRRFVATQAAVPAAEELAFTDSLITRNFSNYSSWHYRSTLLPQLHPQPDSGPQGRLPEDQLLKELELVQNAFFTDPNDQSAWFYHRWLLGRADPQDALRCLHVSRDEACLTVSFSRPLLVGSRTALLLLVDDSPLAVEWRTTPDGRNRSHVWLCDLPAASINDQLPQHTFRVIWTAGDAQKECVLYKGRQEGWCRDSATDQELFRSELSVEKSTVLQSELESCKELLELEPENKWCLLTIILLMRALDPLGYEKETLQYFQTLKAVDPMRAAYLDDLRSKFMLENSILKMEYAEVRVFHLGHKDLTVLCHLDQLLLVTHIDLSHNRLRTLPPAFAALRCLEVLQANDNAIESLDGVTNLPKLQEVLLCNNRLSQLAALQPLASCPKLVLLDLRGNPCTAAVGVLSELAELLPSVSDLLL

Ligand/Cofactor

PLP

CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O

Validation Metrics

PLDDT	86.2
NLMSIM	90.0
AACOMP	90.2
Seqdif (SeqID)	9.2 (XP_003901688.1)
Structdif (F-Target)	4.6 (1ltx A)

ProtNLM

Name	Score
Geranylgeranyl transferase type II subunit alpha	0.377
Geranylgeranyl transferase type-2 subunit alpha	0.314
2.5.1.60	0.227
Rab geranyl-geranyltransferase subunit alpha	0.030
Rab geranylgeranyltransferase subunit alpha	0.011
Rab GGTase alpha	0.007