M4OT2

Prompt

1.4.1.24

Oxidoreductases. Acting on the CH-NH2 group of donors. With NAD(+) or NADP(+) as acceptor. 3-dehydroquinate synthase II.

AI Generated Sequence

365 AAs

MKRIWLKADSGVGDWEEKQRRITEGLEAGVDWVLVDPEDVERVRELGNITVAGFADADADKVVVGDEDEPLPFSGADLSTLRKKDGPVRGAYVRIKDSKYEEFAQMAGKACDYTILVGKDWKIIPLENIIAELQGEITKIIAGVQTAAEAKAAFETLEHGADGVLLDSDDPQEIKRTIEAAERSELLEYKAVTKVEPVGMGDRVCIDTCGSLMQGEGMLVGSMSRGMFLVHSETVESPYVASRPFRVNAGAVHAYIRVPDGKTNYLSELASGDQVLVVDSNGHTRNAIVGRVKIEKRPMLILDAEVEGDTIRTLLQNAETIKLVGKDGKTPSVAELKPGDKVLVHLEEGARHFGMKKIEETIIEK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.4
NLMSIM	70.0
AACOMP	92.2
Seqdif (SeqID)	39.9 (MDO9516541.1)
Structdif (F-Target)	27.6 (2h6r A)

ProtNLM

Name	Score
DHQ synthase	0.434
3-dehydroquinate synthase II	0.198
1.4.1.24	0.159
3-dehydroquinate synthase	0.159
4.2.3.4	0.016
3-dehydroquinate synthase homolog	0.003