M4NFB

Prompt

1.5.1.37

Oxidoreductases. Acting on the CH-NH group of donors. With NAD(+) or NADP(+) as acceptor. FAD reductase (NADH).

AI Generated Sequence

472 AAs

MTKPHIVVIGGGLNGCGIALDKLGRGKVNVTLVDRNNFHTTQSLLHSVAAGRLEPEIAEYPFRSLLAERNHVEFLRMAEVHDVPAKKIVSLPDGKELAYDYLVIATGATANYFGIPGWEENAIGLKTLPDAINIRTHLLNAFERASLETDPEEREALLTFAVVGGGFTGVELAGEIAELTRHQLKTDFPRIDLNTVNVTLVQAGPRILPAFPEEISAKAAKALMKRGVEVRLGTRVKDVDGDYLKTKDGSFIPATTVIWTAGVNANPFGDEIGLETDRAGRVLVDENLTVPGDDEIFAIGDVASMVQPDGKPVGPTAQVAQQMGKYLAKNIKARLDGKPLKPFHYHDLGSLTSIGGKSTVAELLGKMLFGGVPWWLWKMAHYRTLIGFENRLVVMGDWVMYYTYGDRGLRLIIGRDKLKDEEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.0
NLMSIM	70.0
AACOMP	89.6
Seqdif (SeqID)	50.2 (WP_241918026.1)
Structdif (F-Target)	6.5 (5na4 A)

ProtNLM

Name	Score
NADH dehydrogenase	0.197
NAD(P)/FAD-dependent oxidoreductase	0.171
Pyridine nucleotide-disulfide oxidoreductase	0.139
1.6.99.3	0.134
Pyr_redox_2 domain-containing protein	0.066
FAD-dependent pyridine nucleotide-disulfide oxidoreductase	0.040