M4JX6

Prompt

1.1.1.37

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. malate dehydrogenase.

AI Generated Sequence

311 AAs

MKVAVLGAAGGIGQALALLLKTQLPAGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFGGEDPTPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVEKVAKTCPKALVGIITNPVNTTVPIAAEVLKKAGVYDKNRLFGVTTLDVIRSETFVAELKGKQPADVRVPVIGGHSGVTILPLLSQVPGVSFTEEEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVKALQGEKGVVECAYVEGDGQYARFFSQPVLLGKNGVEERLPIGTLSAFEQNALDGMLPTLKGDIALGEEFVK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	93.2
NLMSIM	85.0
AACOMP	91.4
Seqdif (SeqID)	7.1 (WP_001517183.1)
Structdif (F-Target)	1.2 (2pwz C)

ProtNLM

Name	Score
Malate dehydrogenase	0.570
1.1.1.37	0.427
Homoserine dehydrogenase	0.000
NAD-dependent malate dehydrogenase	0.000
2.3.1.8	0.000
L- Malate dehydrogenase	0.000