M48Z6

Prompt

1.5.5.3

Oxidoreductases. Acting on the CH-NH group of donors. With a quinone or similar compound as acceptor. hydroxyproline dehydrogenase.

AI Generated Sequence

352 AAs
MKRKDTPGNAQQKAGKDKTLTGQEEAADRFRGALFDEAVLETYKEQYADSGPYKHGVISGLMEDNLLRSVRQEIRENVHFTPKETDIYKVHQSGDLANLDGLDDDALSRLPSLLALRDAMYSESFRGYLSEVTGCGPLSGKKTDMAINVYTPGCHLLCHDDVIGSRRVSYILYLTDPDLPWAQEWGGALRLYPVETKEGGKVKVPPDLSKVIPPAWNQLSFFAVQPGESFHDVEEVYHAAGGEEVDGGRVRMAISGWFHIPQEGEEGYIEGAEELALNQASLLQLQGQNQLDYYPVQGQTIAEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT83.2
NLMSIM65.0
AACOMP84.1
Seqdif (SeqID)29.2 (KAH6627984.1)
Structdif (F-Target)16.7 (4jzr A)

ProtNLM

NameScore
Fe2OG dioxygenase domain-containing protein0.680
P4Hc domain-containing protein0.035
Oxidoreductase0.029
Oxoglutarate/iron-dependent dioxygenase0.026
Oxoglutarate and iron-dependent oxygenase degradation C-term-domain-containing protein0.017
2-oxoglutarate and Fe(II)-dependent oxygenase superfamily protein0.015
Designed by MP, using an AMD MI250 GPU