M3WGE

Prompt

6.3.2.37

Ligases. Forming carbon-nitrogen bonds. Acid--amino-acid ligases.(peptide synthases). UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase.

AI Generated Sequence

500 AAs

MKILELLKENPEIEISGITTDSREVKPGDTFFALKGAKFDGHKYIQEAIENGAVTIVAEKPLEIPVDVPAIVVPDPRKAMGYLAAAFYGHPSKDLIVIGVTGTNGKTTTAYMIEAILEAAGYKTGLLSTIGYKIGDEIIESGLTTPDPIELQRMLREMVENGCTHAVMEASSHALAQHRVHGCDFDVAVFTNLTQDHLDYHGTMEDYFAAKARLFQTLKPSKAVINLDDPYGELVKEATPEIEVITYGLDKDADVRAENIEMTPEGTSFKLHGPFGETEVESKLIGRFNVYNALAAIAVGLAAGIDLEKIAEGLEHITGVPGRMERVTAGQPFTVIVDYAHTPDALENVLTAAREITPGRIICVFGCGGDRDRTKRPQMGEIAAELADVVILTSDNPRTEDPEAILADIEAGIERAENVYEIIPDRKEAIRRAIEMAEPGDIVLIAGKGHETYQIIGEGKEYPFDDREVAREALERIGHEYEEEEEEEEEEEEEEEEEEE

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	95.2
NLMSIM	85.0
AACOMP	89.3
Seqdif (SeqID)	43.6 (WP_307402774.1)
Structdif (F-Target)	8.7 (4c12 A)

ProtNLM

Name	Score
UDP-MurNAc-tripeptide synthetase	0.203
Meso-diaminopimelate-adding enzyme	0.195
6.3.2.13	0.167
UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase	0.139
UDP-N-acetylmuramyl-tripeptide synthetase	0.103
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase	0.095