M3KKY

Prompt

1.2.1.70

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. glutamyl-tRNA reductase.

AI Generated Sequence

489 AAs

MTLLAVGLNHRTAPVAVLERLAFGPDALPKLLQRLRAEPGVAEAVVLSTCNRVELYASVERLHAAAEALTDWLCDHSGLPVEELTPHLYVHEDDAAVEHLFRVACGLDSMVLGETQILGQVKDAYLRAQDVHAVGPVLNHLFQQALTVGKRAHTETAIDEAPVSVVSYAVGLARRIFGDLAGRTVLVLGAGEMGELTARHLVDHGAGQVTVANRTLERAVALAEELGGEAVPLADLPAALAEADIVLSSTGARHPVLTGEMVARAMRQRRHRPMFLVDIAVPRDLEPRVGELPGVYLYDIDDLQGVAEANLAERRAALEKIETMIAEELGDFAAWLRSLGATPTVRALRDKAETIRTETLARLDRLHPDLSEEQRAVLELLARTVVNQLVHDPTVRLKAAAERDGGAELVAALQELFDLEPDVVAAVAELDVEPADVELAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	92.3
NLMSIM	85.0
AACOMP	82.9
Seqdif (SeqID)	49.5 (WP_213484990.1)
Structdif (F-Target)	9.2 (4n7r A)

ProtNLM

Name	Score
1.2.1.70	0.365
Glutamyl-tRNA reductase	0.350
GluTR	0.280
Hydroxymethylbilane synthase	0.000
Multifunctional fusion protein	0.000
Glutamate-5-semialdehyde dehydrogenase	0.000