M3DVE

Prompt

1.13.12.5

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases). Renilla-type luciferase.

AI Generated Sequence

514 AAs

MTTPTPPRPLRLADFLPCVSGHNPGAWRHPDTDRPQYNRLKYWYTLARLAERGLFDAIFHADTVGVGNIYGDEALRHSIQGGVNPMLLLSALAAVTEHIGLGATTSTTVYEPYPFARRFSTLDHTLRGGRAGWNVVTGYLDSAARNLGFSQPVAHDRVRYAIPEYLQVCKYLWESWEDDAFVLDAERGLYFDPSTFRPAHHEGKAFQVRGYNLSEPSPQRPPVLVQAGASDAGRAFAERAEACFTSAQQNLATGRQTVDAIRAAVAADGRDPDDIRIFMGLTVLVGRTDEPAALIKERLAALVDDEAGVLLLFSGTIDHDFSAYLDEPFLQELYAAEAIKSAHEAFTADWDRRNPLTVRELVEWISGLRGYPVVVGTPAQIAEDLQRWFEEGGCRGFNIAYNPTLPGSTDVFEAVPPELRRRRGFYPEYGGTTLRDHLFGLGPPVAPAPGHAAAYRWTAFAARPAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT	80.6
NLMSIM	85.0
AACOMP	86.5
Seqdif (SeqID)	52.8 (HVX32178.1)
Structdif (F-Target)	8.7 (5w4z A)

ProtNLM

Name	Score
Monooxygenase	0.174
LLM class flavin-dependent oxidoreductase	0.138
Bac_luciferase domain-containing protein	0.074
Nitrilotriacetate monooxygenase component A	0.066
N5,N10-methylene tetrahydromethanopterin reductase	0.055
1.14.-.-	0.050