M3B3X

Prompt

1.2.1.12

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).

AI Generated Sequence

500 AAs

MTIKVGINGFGRIGRNFFRAIQERGLDIVAVNDLTDTETLAHLLKYDSIHGRFDGTVEHTGESITVDGKTIKVFAERDPANLPWGDLGVDIVIESTGVFTDREAAEAHIEAGAKKVVISAPAKGEVDTIVYGVNHDLYDPAKHRIVSNASCTTNCLAPVAKVLHDNFGIEKGLMTTVHAYTNDQNLLDGPHKDLRRARAAAGNIIPTSTGAATAVALVLPELKGKLNGFAIRVPVPDGSVVDLVAELGKETTVEEVNAALKAAAEGPLKGILGYTEDELVSSDFIGSTHSSIVDAPLKMVIEDGLVKVVSWYDNEYGFSNRLVDLTAFVGKDLGRSAPLNMVLTETGAATAVAKALPELKGKLTGNSIRVPTPDVSLAILNLSLEGETTREEVNAYLREVALESPLRRQIDYTESPEIVSSDFVGSRHAGIVDANATIVDGDRAVLYVWYDNEFGYSCQVVRVAEHLAGVRYRTYPREAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	76.6
NLMSIM	90.0
AACOMP	92.5
Seqdif (SeqID)	27.5 (WP_297358370.1)
Structdif (F-Target)	4.5 (3dbv O)

ProtNLM

Name	Score
1.2.1.-	0.476
Glyceraldehyde-3-phosphate dehydrogenase	0.465
1.2.1.12	0.040
Type I glyceraldehyde-3-phosphate dehydrogenase	0.007
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase	0.001
Gp_dh_N domain-containing protein	0.001