M36F4

Prompt

1.1.1.18

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. inositol 2-dehydrogenase.

AI Generated Sequence

386 AAs

MTIRVGILGAGRIGRVHAANIAAHPDAELVAVADPVHPAAAALAAELGAPRAYADVDAVLADPAIDAVLIASPTDTHADLAIRAAEAGKHVLCEKPIALDLARARECIDAVEAAGVPCMVGFNRRFDPGFAALKARVAAGEIGEPPHLVITSRDPGAPPVAYIAVSGGMFRDMMIHDFDMARWLMGDGVEVVYATGSVFVDPAIGAAGDVDTASVTLRTADGAIGHINSSRRAAYGYDQRFEVFGSKGMVQANDITPTTVRVAGAEGAAAHAPYEFFLERYADAYALELAHFVDAVRAGEPPAVGFEDGLRAQLLAEAAERSAREGRPVRLDEGILGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	82.6
NLMSIM	90.0
AACOMP	82.0
Seqdif (SeqID)	40.4 (KAF1028696.1)
Structdif (F-Target)	9.1 (3ezy B)

ProtNLM

Name	Score
Inositol 2-dehydrogenase	0.584
1.1.1.18	0.289
Myo-inositol 2-dehydrogenase	0.050
Myo-inositol 2-dehydrogenase 1	0.015
Myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase	0.010
Myo-inositol 2-dehydrogenase/D-chiro-inositol 1-dehydrogenase	0.004