M336Q

Prompt

1.20.4.4

Oxidoreductases. Acting on phosphorus or arsenic in donors. With disulfide as acceptor. arsenate reductase (thioredoxin).

AI Generated Sequence

106 AAs
MSDIIHLTDASNFDDVLKSDGVVLVDFWATWCGPCRQIAPVLDEIAAEYAGKVKVAKLNVDENPATAAKYGVRGIPTLMLFKDGQEAEQKVGANPKAQLTAFLDSL

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT85.2
NLMSIM95.0
AACOMP91.5
Seqdif (SeqID)26.9 (WP_133588174.1)
Structdif (F-Target)5.0 (4ba7 B)

ProtNLM

NameScore
Thioredoxin0.994
Thioredoxin 10.001
Thioredoxin TrxA0.001
Thioredoxin domain-containing protein0.001
Thiol reductase thioredoxin0.000
Thioredoxin 20.000
Designed by MP, using an AMD MI250 GPU