M2RI8

Prompt

1.2.1.72

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. erythrose-4-phosphate dehydrogenase.

AI Generated Sequence

393 AAs

MTGLPLRIAINGYGRIGRCVLRALFERHGARYFDIVAINDLADPAALSYLTRFDSTHGRFPGEVRCDGEQLLINGDGIRVLRESTPEALDWAHSGVDLVLECSGAYHTREDGQRHLDAGAKKLLFSQPAASADVDATIVYGVNHDTLTAAERLVSNASCTTNCIVPLLRVLDDALGIEHGSITTIHSAMNDQQVIDAYHADLRRTRAASQSIIPVDTGLARGIERILPQLAGRFQAKAVRVPTVNVSAMDLTVTTGRDVTVDEVNRILRAAAHGTLRGILDYTEAPHASCDFNHDPHSAIVDGTQTRVSGPRLVKLLVWCDNEWGFANRMLDVADLMAAHARGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.1
NLMSIM	70.0
AACOMP	84.9
Seqdif (SeqID)	24.3 (WP_028631899.1)
Structdif (F-Target)	4.8 (2x5k Q)

ProtNLM

Name	Score
1.2.1.72	0.194
1.2.1.12	0.190
Glyceraldehyde-3-phosphate dehydrogenase	0.177
Erythrose-4-phosphate dehydrogenase	0.168
D-erythrose-4-phosphate dehydrogenase	0.066
Erythrose 4-phosphate dehydrogenase	0.043