M2R0X

Prompt

1.14.99.1

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. Miscellaneous. prostaglandin-endoperoxide synthase.

AI Generated Sequence

499 AAs

MRYVLTFHGWLWNIVNGITFLRDALMRLVLTSRSHLIPSPPTYNSHYGYKSWEAYSNLSYYTRTLPPVPLDCPTPMGVKGKKELPDVKLLAEKFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSDKKGPGFTKALGHGVDLGHIYGETLERQHKLRLFKDGKLKYQVLDGEMYPPTVKETQAEMHYPPHVPESQQLAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPTWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYYFKLKFDPELLFNQRFQYQNRIAMEFNTLYHWHPLMPDTFHIDGQEYSFQQFLYNTSIMLHYGISHMVDSFSKQSAGRVAGGRNVPAAVLKVAVASIKESRQMRYQSFNEYRKRFGMKPYKSFQELTGEKEMAAELEELYGDIDAVELYPGLLVEKPRPNAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGKVGFDIVNTASLQKLICLNVKGCPYVASFHVPDP

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	82.1
NLMSIM	95.0
AACOMP	92.8
Seqdif (SeqID)	14.6 (NXF12109.1)
Structdif (F-Target)	5.4 (5ikv A)

ProtNLM

Name	Score
Prostaglandin-endoperoxide synthase	0.428
1.14.99.1	0.227
Prostaglandin G/H synthase 2	0.094
Prostaglandin H2 synthase 2	0.073
Cyclooxygenase-2	0.062
Prostaglandin H2 synthase 1	0.035