M2QJL

Prompt

2.5.1.10

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. (2E,6E)-farnesyl diphosphate synthase.

AI Generated Sequence

685 AAs

MATTTLKKFLAVFPVLKEELLEHLKSYNLPDEALRWYKRSLNYNVLGGKCNRGMSVPDTYVLLLGKPLTDEEYFKAATLGWCIEWLQAFFLVSDDIMDSSITRRGQPCWYRLEGVGMIAINDAFMLEAAIYTILKKYFRSHPYYVDLIELFHEVTFQTELGQLCDLLTAPEDKVDLSKFSMEKHKFIVIYKTAYYSFYLPVALALYYMGLATPKNLKQAEDILIELGEYFQIQDDYLDCFGLPEYIGKIGTDIMDNKCSWLVNQALARATPEQRKILEENYGCKDPANEAKVKKLYNELKLEQVYREYEEKCVYELINAINAIDESQGLKKEVFLAFLAKIYKRTKDKFQAAFPVLVEDLLADAKSYNLPEEALRWYKRVLDYNVLGGKLNRGMSVVDTYKILLGKPLTDEEYFKAATLGWCIELLQAFFLVADDIMDSSITRRGQPCWYRLEGVGMIAINDAFMLEAAIYTLLKKYFRSKPYYVDLIELFHEVTFQTELGQMLDLITAPEGKVDLSKFSMEKYYRIVIYKTAYYSFYLPVALALYMAGLETPKNLKQAVDILIEMGEYFQIQDDYLDCFGTPEYIGKIGTDIMDNKCSWLVNQALARATPEQRKVLEENYGQKDPANVAKVKALYNELKLEQRYAEYEQKCYGELIAAINAHDSQGLKKEVFLAFLAKIYKRTK

Ligand/Cofactor

FPP

CC(=CCCC(=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C)C)C

Validation Metrics

PLDDT	88.6
NLMSIM	60.0
AACOMP	91.2
Seqdif (SeqID)	21.3 (KAK4110784.1)
Structdif (F-Target)	3.2 (7bux A)

ProtNLM

Name	Score
Farnesyl pyrophosphate synthase	0.525
Farnesyl diphosphate synthase	0.074
Polyprenyl synthetase	0.039
Farnesyl pyrophosphate synthase 1	0.033
Terpenoid synthase	0.028
Farnesyl pyrophosphate synthetase	0.019