M2J3C

Prompt

1.13.11.53

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. acireductone dioxygenase (Ni(2+)-requiring).

AI Generated Sequence

186 AAs
MSILVKHEDTTPETPHVDSRDGELIGTELNKIGVAFERWEASAEIEDDAAQEEVIAYAKADIDRIVGERGFKTRDVISIASDNPKLEELRAKFLDEHHHTEDEVRFFVEGSGLFTLHVDGKVFQIECEKDDLISVPAGTLHWFDMGPEPHVTAIRFFTEPEGWVGHFTGTDIAKQFPRYEEDKPHA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT79.9
NLMSIM90.0
AACOMP88.9
Seqdif (SeqID)27.6 (WP_017155308.1)
Structdif (F-Target)14.5 (4qgm A)

ProtNLM

NameScore
1.13.11.540.119
ARD'0.113
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase0.104
Acireductone dioxygenase (Ni(2+)-requiring)0.104
ARD0.095
Fe-ARD0.093
Designed by MP, using an AMD MI250 GPU