M2FC5

Prompt

2.7.11.21

Transferases. Transferring phosphorus-containing groups. Protein-serine/threonine kinases. polo kinase.

AI Generated Sequence

499 AAs

MSFFNRQRLKFLGSPEKKKQYEHVRRDLNPEDFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDATMLELERPLTEPQIKVVCRQTLEALNYLHENKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGITLIEMAQIEPPHHEMNPMRVLLKIAKSEPPTLAQPSKWSSDFKDFLKKCLEKNPEARWSTSQLLQHPFVTVTDNKPLRELIAEAKAEVTEEVEDGKDEEEEEETENSLQLPIAKRASSDVSIASSSEDKLSQNACIVESVSEKTETSTSGEKFSNKILNEKPCTEGEKADVVEGMHDNTENMEAMQLDHLAAVVRPKERNTTERPEKKRPLDLPEDTQEQTDDVVNSEKEENTLMTENKLKKQYEERQRQLERQFKKKNEKLQDHQELLQQELEEQ

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	77.2
NLMSIM	60.0
AACOMP	89.8
Seqdif (SeqID)	15.6 (XP_028730491.1)
Structdif (F-Target)	2.6 (4usd A)

ProtNLM

Name	Score
2.7.11.1	0.529
Non-specific serine/threonine protein kinase	0.308
SLK kinase	0.130
STK10 kinase	0.005
Serine/threonine-protein kinase 10	0.003
STE20-like kinase	0.002