M2CV7

Prompt

1.1.1.271

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. GDP-L-fucose synthase.

AI Generated Sequence

367 AAs

MTKDSRIFVAGHRGMVGSAIVRALERRGYTNLITRTHDELDLTNQAAVRDFFAAEKPDYVFLAAAKVGGIVANNTYPADFIYENMLIEQNVIHAAYLNGVKKLLFLGSSCIYPKLAPQPMKESELLTGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPNDNFHPLNSHVLPALIRRFHEAKANGAPEVVVWGTGTPLREFLHVDDMADACVFVMNLYTPELMHVNVGTGVDCTIRELAQTVAKVVGYKGEIVFDTSKPDGTPRKLMDVSRLHALGWTHKVSLEEGLAATYRWFLENQDFRVRGGLGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.0
NLMSIM	70.0
AACOMP	86.5
Seqdif (SeqID)	23.3 (MDB8117725.1)
Structdif (F-Target)	4.4 (1bsv A)

ProtNLM

Name	Score
GDP-L-fucose synthase	0.468
GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase	0.320
1.1.1.271	0.203
GDP-L-fucose synthetase	0.001
NAD-dependent epimerase/dehydratase family protein	0.001
GDP-6-deoxy-D-mannose-3,5-epimerase-4-reductase	0.000