M26DK

Prompt

1.1.1.3

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. homoserine dehydrogenase.

AI Generated Sequence

480 AAs

MTEPLRLGIAGLGTVGAGVVRIVQRHADLLAARAGRPIEIAAVSARSRDKDRGVDLSGYAWEDDPVALARRDDVDVVVELIGGDDGPAKAATEAAIAAGKDVVTANKAMLAHHGQELAEAAEAAGRALRFEAAVAGGIPVIKGLTEGAAGNEITRVMGVMNGTCNYILTRMEASGRDYATVLAEAQALGYAEADPTLDVEGIDAGHKLALLAAIAFGTQVDFDGVELEGIGRIVLDDIRHAADLGYRIKLLGVAQMTGRGLEQRMHPCLVPASSPLGQVEGANMAVVAEGDAVGQVVLRGPGAGEGPTASAVVADVIDIARGVRVPTFGQPAAALARPAPAAAAPPAPAYYLRMTLEDRPGALAEIAAALGEAGVSIDRMIQYGRDGEAPVVLVTHRGTPAALDAALAEIEATTVIAGRPVVMRIEELGEGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	84.2
NLMSIM	85.0
AACOMP	82.6
Seqdif (SeqID)	23.9 (WP_088217136.1)
Structdif (F-Target)	8.6 (3mtj A)

ProtNLM

Name	Score
Homoserine dehydrogenase	0.541
1.1.1.3	0.455
Aspartokinase	0.001
2.7.2.4	0.001
HDH	0.000
Bifunctional aspartate kinase/homoserine dehydrogenase I	0.000