M25I7

Prompt

1.14.13.35

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. anthranilate 3-monooxygenase (deaminating).

AI Generated Sequence

490 AAs

MRRLLLLGGGYAGLAAARALARRLGRDADYEVVLVDRRNFHCFTPLLHLAATGSLEPGSIDEPIRGILARRHDVRFRQGEVTRIDRARRRVVLAPGEEVAYDYLVLALGSHANYFGIPGLAEHAIGMKDLDDALRIRHRLLAQFERAHVLTTDPERRRALTFAIVGGGPTGVELAAELHDMVLDTLVRDYPNIDRNEIRITLIEAGERILPAFPERLSAYAQEHLTKLGVDVLTGTRVASVDGRGVRTGGEIEADTMVWTAGIAASPVFGDALGLEQNRAGRLVVDPTLQVIGHDDVYAVGDLCAMVQPDGTRHVPTVAQAAHQAGRYLGRNLAARMDGRPLPPFRYRHLGSLVAIGRDAAVAELPWNMLRGFFAGWLWWMVHMRSLVGMRNRMVVLTDWAWNYLFGGQESRIITGRPFTYAHAETMTLEEVRAAAAAGEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	91.0
NLMSIM	60.0
AACOMP	85.2
Seqdif (SeqID)	53.0 (WP_204623715.1)
Structdif (F-Target)	6.2 (4nwz A)

ProtNLM

Name	Score
NADH dehydrogenase	0.232
NAD(P)/FAD-dependent oxidoreductase	0.223
1.6.99.3	0.082
NADH dehydrogenase FAD-containing subunit	0.066
Pyridine nucleotide-disulfide oxidoreductase	0.063
1.6.99.-	0.052