M24WS

Prompt

2.5.1.56

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. N-acetylneuraminate synthase.

AI Generated Sequence

499 AAs

MSLDIGNRVIGPNDPVFIIAELGANHNGSLDTALKLIDAAVEAGADCVKFQTFTPESMTLDSKRPYQIRSGVWGGRTLYDLYKELELTEDEHEELFRYCRELGIDFLSTPFDETSVDFLEELDVPAYKIASGEITDFPLLKRVAATGKPIIMSTGMATLEEIERAVTVLREAGCNDLVLLHCTSTYPAPAEDVNLRAMPTLQERFPGVPVGYSDHTLGIQVPISAVALGATVIEKHFTLDRSLPGPDHRASLEPDELKSLVQDIRTVEQALGDGIKRVPSQEVKNMRFARSLVAARDIAAGEVLTEENVLARRPGTGLHPRHYDGILGRTAKRDVAKGEPLTWDLIDRSLLKGELLGKGELIKLTKCQVDKHGKDLPLPHLVELAETHGCDVALLHCTSTYPAPAEDVNLRAMPTLQEAFPDVRIGYSDHTLGIQSPIAAVALGATVIEKHFTLDRSLWGPDHRASLEPDELKALVRDIRTVEQALGDGIKRVTPQEAN

Ligand/Cofactor

PLP

CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O

Validation Metrics

PLDDT	89.5
NLMSIM	90.0
AACOMP	94.7
Seqdif (SeqID)	44.1 (AXI25871.1)
Structdif (F-Target)	11.1 (2wqp 2)

ProtNLM

Name	Score
N-acetylneuraminate synthase	0.480
AFP-like domain-containing protein	0.173
2.5.1.56	0.101
N-acetylneuraminic acid synthase domain-containing protein	0.033
Acetylneuraminic acid synthetase	0.032
Sialic acid synthase	0.027