M1SGF

Prompt

1.1.1.43

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. phosphogluconate 2-dehydrogenase.

AI Generated Sequence

500 AAs

MSKSDIGLIGLAVMGQNLILNMVEKGFKVSVFNRTTEKTDEFLKNAEKGTNFVGAYSIEEFVESLKRPRKIMLMVKAGKPVDAFIEQLVPLLDKGDIIIDGGNSNFTDTIRRTEYLRSKGIHFIGTGVSGGEEGARFGPSIMPGGNKEAWEHIKPIFQAIAAKVDGEPCVTYIGPDGAGHFVKMVHNGIEYGDMQLICEAYHLLKHVLGLSNDEMHKIFTEWNKGELDSYLIEITADILFYKDELTGKPLVDKILDTAGQKGTGKWTGINALDLGVPLTLIGESVFARSLSSLKDERVKASKVLSGPKTEFKGDKKAFIEDVRQALYASKICSYAQGFMLMRQASEEYGWNLNYGEIALMWRGGCIIRSVFLGKIKDAYDRNPDLKNLLLDPFFKDIIENSQDAWRKVVSLGVQNGIPTPGFTAALAYFDGYRTERLPANLLQAQRDYFGAHTYERVDKPRGEFHTNWTGRGGEVTSSTYNADVSKKKKKKKKKKKKKKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	91.4
NLMSIM	62.6
AACOMP	92.0
Seqdif (SeqID)	26.9 (NLW55523.1)
Structdif (F-Target)	1.7 (5uq9 E)

ProtNLM

Name	Score
1.1.1.44	0.626
6-phosphogluconate dehydrogenase, decarboxylating	0.366
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)	0.002
NADP-dependent phosphogluconate dehydrogenase	0.002
6PGD domain-containing protein	0.001
Glucose-6-phosphate 1-dehydrogenase	0.000