M12J6

Prompt

1.2.1.28

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. benzaldehyde dehydrogenase (NAD(+)).

AI Generated Sequence

499 AAs

MSSTVTLPPPNGKLYQEPLGLFINNEFVDSVSGKTFETINPSTEKVIAQVAEGGEEDVDLAVKAARDAFDLGPWRKMTASERGRLLNKLADLIEQNLEILAALESLDNGKPYAYSMADVGGAISCIRYYAGWADKIHGQTIPIDPGTFAYTLHEPIGVCGQIIPWNFPLLMASWKIGPALAAGNTVVLKPAEQTPLSALYVAQLIKEAGFPPGVINIVPGYGRVAGAAISSHMDIDKIAFTGSTVVGRLIMKAAASNLKRVTLELGGKSPNIVFSDADLDKAVEWAAFGIFYNSGQVCTAGSRLYVQESIYDKFVERFKERVKNWKVGDPFDEKTFQGPQISKAQFDKILSYIESGKSEGAKLLTGGERHGDKGYFIQPTVFSNVTDDMRIAKEEIFGPVVCVQKFKTVEEVIKRANDTEYGLAAGVFTKDLNKAIRVSNALQAGTVWINCYNLLHAQVPFGGYKQSGIGRELGEYGLNNYTQVKTVTIKLSSKSPWGF

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	93.2
NLMSIM	80.0
AACOMP	94.7
Seqdif (SeqID)	30.7 (XP_024683798.1)
Structdif (F-Target)	2.4 (6alj A)

ProtNLM

Name	Score
Aldehyde dehydrogenase	0.314
Aldedh domain-containing protein	0.126
Aldehyde dehydrogenase (NAD+)	0.116
Aldehyde dehydrogenase (NAD(P)(+)) ald5	0.050
Aldehyde dehydrogenase X, mitochondrial	0.046
Aldehyde/histidinol dehydrogenase	0.042