M0YXS

Prompt

1.14.19.79

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. 3beta,22alpha-dihydroxysteroid 3-dehydrogenase.

AI Generated Sequence

256 AAs

MDLSLLERDLLSLCLGLLAAVGQFIVLLELVPSRYGRYESRSPGYRVRPRCAWFVQELPSLLVPLGLLLARAPRLSGLWPGLLLGCMFCHYFHRSLIFPLFIRGGRPVPLQTFAKAMLFCCYNGYLQGRYLSHCAEYAPDCWTDPRFSVGVLLWLLGMGINIHSDHILRNLRKPGETGYKIPQGGLFTYVSGANYFGEIVEWGFALAASWSVPAVAFAFFTFTVLGPRAAEHHRWYLREFTDYPKRRRALIPIFIF

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	87.9
NLMSIM	62.8
AACOMP	89.2
Seqdif (SeqID)	37.3 (XP_010579556.1)
Structdif (F-Target)	6.3 (7c83 A)

ProtNLM

Name	Score
1.3.1.22	0.628
3-oxo-5-alpha-steroid 4-dehydrogenase	0.184
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+))	0.104
S5A_REDUCTASE domain-containing protein	0.025
SR type 2	0.011
1.3.99.5	0.006