M0YVA

Prompt

1.1.1.86

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. ketol-acid reductoisomerase (NADP(+)).

AI Generated Sequence

339 AAs

MAVIYDEDADLSLIKGKKVAVIGYGSQGHAHALNLRDSGVDVVVALRPGSASWAKAEAAGLKVAEVAEAAKQADVVMILTPDEFQSQVYRDEIEPNLKQGATLAFAHGFNIHYGQIVPRADLDVIMVAPKAPGHTVRSEFTNGGGVPDLIAIHQDASGNAKNLALSYASAVGGGRTGIIETSFREETETDLFGEQAVLCGGTVELIQAGFETLTEAGYAPEMAYFECLHELKLIVDLMYEGGLANMNYSISNNAEYGEYVTGPRVINEESRKAMRNALKDIQDGEYAKMFILENATGYPEMTARRRNNAAHPIEQVGGKLRAMMPWIAANKIVDKAARA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	92.2
NLMSIM	70.0
AACOMP	92.6
Seqdif (SeqID)	16.1 (MBS7325630.1)
Structdif (F-Target)	3.1 (4tsk A)

ProtNLM

Name	Score
AHIR	0.219
Ketol-acid reductoisomerase (NADP(+))	0.177
Alpha-keto-beta-hydroxylacyl reductoisomerase	0.174
1.1.1.86	0.139
KARI	0.129
Acetohydroxy-acid isomeroreductase	0.122