M0WL2

Prompt

6.3.2.8

Ligases. Forming carbon-nitrogen bonds. Acid--amino-acid ligases.(peptide synthases). UDP-N-acetylmuramate--L-alanine ligase.

AI Generated Sequence

286 AAs

MKIKKIYFIGIGGYGMSAIAEILLNLGYKVQGSDIKESEITKKLEELGIEIFIGHKAENIKDVDLVVYSTAFPKDNVEIIEAKKKNIPIIKRAEMLGELMKEFTSIAVAGAHGKTTITSMLAHILDKAKLDPTILIGGELANAGTNAKLGKSEFLVAEADESDRSFLTLHPDIAVITNIDADHLDCYKDLDKIKEAFVEFANKIPFYGKAIICADDENVREITPEIKRPVITYGLNENADVRATNIKMENGSTTFDVFHKGEKLGDIVLPVPGKHNILNALAAIAV

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	96.9
NLMSIM	90.0
AACOMP	88.5
Seqdif (SeqID)	38.9 (HXE98276.1)
Structdif (F-Target)	5.6 (6cau A)

ProtNLM

Name	Score
UDP-N-acetylmuramate--L-alanine ligase	0.440
6.3.2.8	0.327
UDP-N-acetylmuramate--alanine ligase	0.164
UDP-N-acetylmuramoyl-L-alanine synthetase	0.016
MurF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine	0.009
UDP-N-acetylmuramate-alanine ligase	0.007