M02FU

Prompt

1.7.1.7

Oxidoreductases. Acting on other nitrogenous compounds as donors. With NAD(+) or NADP(+) as acceptor. GMP reductase.

AI Generated Sequence

396 AAs

MKIENDPKLDFKDVLFRPKRSTLKKRSEVDLTRTFTFRHSKKTITGIPIIAANMDTVGTFEMAAVLAEHGMMTAIHKHYSVEEWKAFVAKHPEVLHHHVAVSGGTSDADFKKLTAIVKGHPQIKFICLDVANGYSHVFVDFVKDVRKKFPHHTIMAGNVATGEMTEELILAGADIIKVGIGPGAVCTTRKVGAGVGPQLSAVIECADPAHGLKGHIIADGGCTCPGDVSKAFGAGADFVMLGGMLAGHDESGGEIMDENGKVFKMFYGMSSDTAMKKHAGGVAEYRASEGKTVEVPFRGPVEETIKELLGGVRSTCTYVGAAKLKELSKRTTFIRVAQQLNRVFGEGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	85.6
NLMSIM	95.0
AACOMP	83.2
Seqdif (SeqID)	19.7 (XP_016316291.1)
Structdif (F-Target)	1.5 (2c6q H)

ProtNLM

Name	Score
GMP reductase	0.368
1.7.1.7	0.225
Guanosine 5'-monophosphate oxidoreductase	0.185
Guanosine monophosphate reductase	0.107
GMPR	0.097
GMP reductase 1	0.001