M6ZZY

Prompt

1.2.1.39

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. phenylacetaldehyde dehydrogenase.

AI Generated Sequence

503 AAs

MTTPLLPALLARLPALRLGHGLFIGGEWRPALGGARFDVVSPATGEPLATVAAAGAADVDAAVAAARAAFAAGPWAGTPAAERARLLLRFAALIEAHADELAALETLDNGKPIALARAEVDGLALNWLRWYAEAADKIYGQTLPTGPDRLALTRRKEPVGVVAAIVPWNFPLAMAAWKLGPALAAGNSVVLKPSEQTALTALALAELALEAGLPPGVLNVVPGYGAEAGAALTAHPGVAKIAFTGSTRIGKLLLRYAADHLKRVSLELGGKSPFIVLADADLAAAVDAAALGIFLNQGQVCTAASRLYVQEGIADAFVARLVARARAWRVGDGLDPATAIGPLVSAAQRDKVLAYIADGRAEGARLVTGGARPAGLAGGYYVAPTVLAGVTPAMRLAREEIFGPVLAVLPFDDAAEALALANATEYGLAASVWTRDLGRALRVARALEAGTVWVNTHALADAAVPFGGMKQSGNGRDKGAHGLEAYTETKTVWVDVAAAPAGF

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	95.6
NLMSIM	70.0
AACOMP	84.2
Seqdif (SeqID)	39.8 (MDQ3556140.1)
Structdif (F-Target)	3.3 (4zwl C)

ProtNLM

Name	Score
Aldehyde dehydrogenase family protein	0.340
Aldehyde dehydrogenase	0.198
1.2.1.5	0.088
Aldehyde dehydrogenase PuuC	0.081
Betaine-aldehyde dehydrogenase	0.064
Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase	0.042