MK457

Prompt

7.2.1.1

Translocases. Catalysing the translocation of inorganic cations. Linked to oxidoreductase reactions. NADH:ubiquinone reductase (Na(+)-transporting).

AI Generated Sequence

460 AAs

MLKILIPTIMLFPTIWLSKPKWLWTNTTTHSLLIALTSLTWLNWTSETGWTSLNLYFATDPLSTPLLVLTCWLLPLMILASQNHLNPEPLNRQRLYITLLTSLQIFLIMAFSATEIIMFYIMFEATLIPTLIIITRWGNQTERLNAGTYFLFYTLAGSLPLLVALLLLQNQTGTLSLLVLQYSQPLLLNTWSDKIWWAACLIAFLVKMPLYGVHLWLPKAHVEAPVAGSMVLAAVLLKLGGYGMMRMMMVLDPLTKELAYPFIILALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFSGAIILMIAHGLTSSALFCLANTNYERTHSRTMILARGLQMILPLMAVWWFIANLANLALPPLPNLMGELMIITSLFNWSSWTIILTGAGTLITAGYSLYMFLMSQRGPLPSHIIALEPSHTREHLLMALHLIPLLLLITKPELMWGWCY

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	93.8
NLMSIM	70.0
AACOMP	85.2
Seqdif (SeqID)	10.7 (YP_008815821.1)
Structdif (F-Target)	2.0 (7v2c r)

ProtNLM

Name	Score
NADH-ubiquinone oxidoreductase chain 4	0.540
7.1.1.2	0.449
NADH dehydrogenase subunit 4	0.010
NDH-1 subunit M	0.000
NAD(P)H-quinone oxidoreductase chain 4	0.000
1.6.5.3	0.000