MAMXH

Prompt

2.1.1.163

Transferases. Transferring one-carbon groups. Methyltransferases. demethylmenaquinone methyltransferase.

AI Generated Sequence

284 AAs
MSEKERVADVFDSIAPRYDLMNSVLSFGIDRLWRRRTMRALAVRPGQRVLDLACGTGDWSIAFAERVGPSGHVVGLDFSEGMLAVGRERARAAGLSDNIELVQGDAMELPFADNSFDAVTIAFGLRNVPDHRVALREMHRVLKPGGRLVILEFSQPVFPVFSKVYELYFRFAMPVMGRLVSSSPAEYAWLQESIRAWPDQRALAEMFRAAGFARVDYRNLTFGVVALHRGFKLPAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

S-adenosylmethionine

C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

Validation Metrics

PLDDT94.8
NLMSIM90.0
AACOMP81.1
Seqdif (SeqID)43.7 (WP_070121139.1)
Structdif (F-Target)12.2 (4obx B)

ProtNLM

NameScore
Demethylmenaquinone methyltransferase0.487
2.1.1.1630.464
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase0.020
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE0.015
2.1.1.2010.007
Bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE0.003
Designed by MP, using an AMD MI250 GPU