MEJC2

Prompt

1.13.11.39

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. biphenyl-2,3-diol 1,2-dioxygenase.

AI Generated Sequence

303 AAs

MSIRSLGYLRIEATDMAAWREYGLKVLGMVEGKGADPGALYLRMDDFPARLVVVPGEHDRLVEAGWEAANAEGLQEIRNRLEAAGTPFKEATAEELADRRVEEMIRFSDPSGNTLEVFHGAALEHRRYVSPYGHRFVTGEQGMGHVVLTRDDDESALHFYRDVLGFRLRDSMRLPPQMVGRPADGPALWLFFHGCNPRHSLAFLPMPTPSGIVHLMVEVENADDVGLCLDRALRRKVPISATLGRHVNDKMLSFYMKTPGGFDIEFGCEGRQVDDDDWIARESTAVSLWGHDFSVGTRSGLFT

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.3
NLMSIM	70.0
AACOMP	92.3
Seqdif (SeqID)	10.7 (WP_220019805.1)
Structdif (F-Target)	3.9 (2zi8 A)

ProtNLM

Name	Score
2,3-dihydroxybiphenyl 1,2-dioxygenase	0.432
1.13.11.-	0.123
Iron-dependent extradiol dioxygenase	0.101
Extradiol dioxygenase	0.079
Biphenyl-2,3-diol 1,2-dioxygenase	0.061
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase	0.040