M34UB

Prompt

2.5.1.134

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. cystathionine beta-synthase (O-acetyl-L-serine).

AI Generated Sequence

277 AAs

MKIVDSIMELVGNTPLVKLNSVTKGIEATVLAKVEYFNPGGSVKDRIALKMIEDAEASGLLKPGGTIVEPTSGNTGVGLAIVAQQKGYKCIFVCPDKMSTDKRNVLKAYGAEVVVCPTAVAPEHPESYYNVSDRLARETPGAWKPDQYSNPNNPLSHYESTGPEIWKQTDGKITHFVAGVGTGGTISGTGRYLKEVSPDVKVIGADPEGSVYSGGSGRPYLVEGVGEDIFPETYDRSVADEIVAVSDKDSFDMTRRLAKEEGLLVGGSSGMAVVAAL

Ligand/Cofactor

S-adenosylmethionine

C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

Validation Metrics

PLDDT	96.1
NLMSIM	85.0
AACOMP	91.2
Seqdif (SeqID)	11.2 (WP_316748882.1)
Structdif (F-Target)	4.5 (5xeo A)

ProtNLM

Name	Score
Cystathionine beta-synthase	0.570
4.2.1.22	0.248
Beta-thionase	0.055
Pyridoxal-phosphate dependent enzyme	0.030
Serine sulfhydrase	0.012
Cysteine synthase	0.012