MFIJA

Prompt

2.3.1.88

Transferases. Acyltransferases. Transferring groups other than amino-acyl groups. Transferred entry: 2.3.1.254, 2.3.1.255, 2.3.1.256, 2.3.1.257, 2.3.1.258

AI Generated Sequence

500 AAs

MDPQQRLLLEVAWEALEDAGLAPGALRGSRTGVFVGVANNDYGRLLLGDLPGVDGYLATGNAKSFAAGRLSYLLGLRGPSLTVDTACSSSLVAVHLACQSLRSGECDLALAGGVNLLLTPGTFVGFSQAGMLSPDGRCKAFDASADGYGRSEGVGMVVLKRLSDALADGDRILAVIRGSAVNQDGASNGLTAPNGPSQAAVIRQALAAAGLAPADVGYVEAHGTGTALGDPIEAQALGAVFGRGRDAGRPLWLGSVKTNIGHLEAAAGVAGVIKVVLSLHHGVLPPTLHFAEPSPHIDWAALPVRVLTEARPWPAGGRPRRAGVSSFGVSGTNAHVVLEQAPAPAPAAAAAPAPALLPLSARTAAALRAQAGRLAAHLAAGPGAALADVAHTAATGRSAFAHRAAVVGADRAALAAGLAALAAGEPAGVVTGAAGGGRPVAFLFTGQGSQWVGMGRELYAAEPVFAAALDACAAALAPHLDRSLVDVLLGGGGGGGGGGG

Ligand/Cofactor

acetyl-CoA

CC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O

Validation Metrics

PLDDT	92.5
NLMSIM	60.0
AACOMP	84.5
Seqdif (SeqID)	44.2 (WP_159060994.1)
Structdif (F-Target)	18.0 (6mhk B)

ProtNLM

Name	Score
Type I polyketide synthase	0.157
Beta-ketoacyl synthase	0.120
Carrier domain-containing protein	0.117
SDR family NAD(P)-dependent oxidoreductase	0.114
Acyltransferase domain-containing protein	0.097
Acyl transferase domain-containing protein	0.075